Circulating soluble leptin receptor, leptin, and insulin resistance before and after weight loss in obese children
نویسندگان
چکیده
منابع مشابه
Tracking of leptin, soluble leptin receptor, and the free leptin index during weight loss and regain in children.
OBJECTIVE To investigate changes in leptin and soluble leptin receptor (SLR) concentrations, and in the free leptin index (FLI) during weight loss and subsequent weight regain; and to ascertain whether these indices remain stable in the rank of the distribution in repeated measures (tracking) during perturbations of weight in obese children. DESIGN AND MEASUREMENTS In a longitudinal study, 11...
متن کاملLeptin and soluble leptin receptor levels in obese and weight-losing individuals.
To investigate soluble leptin receptor (sLR) in plasma, specific anti-sLR monoclonal antibodies were developed. Western blot analysis and size exclusion fractionation demonstrated sLR in plasma with a molecular mass of approximately 180,000. Next to this, the presence of sLR-leptin complexes in plasma was confirmed. Using the developed monoclonal antibodies, a specific sLR ELISA was developed, ...
متن کاملLongitudinal analysis of leptin variation during weight regain after weight loss in obese children.
OBJECTIVE This study assessed if lower than predicted serum leptin concentrations seen during weight loss persisted during weight regain, with possible implications for weight control. METHODS 115 children were investigated during a 12-week weight loss program. 90 children completed the program, and 68 children entered a follow-up program spanning 28 months. Measurements were performed at bas...
متن کاملEffect of Eight Weeks of Aerobic Aquatic and Land Exercise Training on Leptin, Resistin, and Insulin Resistance in Obese Women
Background: Regular exercise has been shown to improve diabetes-related biological markers. However, for some groups, exercises that require weight bearing are difficult. Therefore, the purpose of the present study was to compare the effect of eight weeks of aerobic aquatic and land exercise training on leptin, resistin, and insulin resistance in obese women. Materials and Methods: In the p...
متن کاملRelationship between Thyroid Volume and Iodine, Leptin, and Adiponectin in Obese Women before and after Weight Loss
Objective: To investigate whether or not reduction of thyroid volume during weight loss is related to adipocytokines and urinary iodine excretion in obese women. Subjects and Methods: 98 obese and 31 non-obese women consecutively admitted to the endocrinology and metabolism outpatient clinic of the School of Medicine, Akdeniz University were included in the study. Thyroid volume, thyroid functi...
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ژورنال
عنوان ژورنال: International Journal of Obesity
سال: 2005
ISSN: 0307-0565,1476-5497
DOI: 10.1038/sj.ijo.0803027